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Sugar's 'tipping point' link to Alzheimer's disease revealed

"For the first time a "tipping point" molecular link between the blood sugar glucose and Alzheimer's disease has been established by scientists, who have shown that excess glucose damages a vital enzyme involved with inflammation response to the early stages of Alzheimer's. Abnormally high blood sugar levels, or hyperglycaemia, is well-known as a characteristic of diabetes and obesity, but its link to Alzheimer's disease is less familiar. Diabetes patients have an increased risk of developing Alzheimer's disease compared to healthy individuals. In Alzheimer's disease abnormal proteins aggregate to form plaques and tangles in the brain which progressively damage the brain and lead to severe c

Women's Final Four brings $100,000 grant for breast cancer research to Dallas

"A Dallas research professor has been awarded $100,000 to study an aggressive form of breast cancer, thanks to the NCAA’s Women’s Final Four tournament. Dr. Angelique Whitehurst plans to use the Kay Yow Cancer Fund grant to help understand why certain cancer cells are resistant to chemotherapy. Every year the Kay Yow fund gives money to institutions in the Final Four host city. The fund collaborated with the V Foundation for Cancer Research to award Whitehurst's grant." To read the full article, click HERE (UT Southwestern Medical Center)

New approach to treating Alzheimer's disease

"As therapeutics for AD, Professor Lim suggested a strategy that uses matal-based complexes for reducing the toxicity of the amyloid beta (Aβ). Althought various metal complexs have been suggested as therapeutics for AD, none of them work effectively in vivo. The research team has found that they can hydrolyze amyloid-beta proteins using a crystal structure, called tetra-N methylated cyclam (TMC). Hydrolysis is the process that uses water molecules to split other molecules apart. The metal-mediated TMC structure uses the external water and cut off the binding of amyloid-beta protein effectively. In this study, the following four metals (cobalt, nickel, copper and zinc) were placed at the cen

This NYFW Show Put Women Affected By Breast Cancer On the Runway

A fashion show that took place Sunday at New York Fashion Week is getting tons of attention—not just for the clothes it displayed, but for the models themselves. The AnaOno X #Cancerland fashion show featured 16 women modeling lingerie—all of whom are either currently battling or have battled breast cancer. The show featured underwear from AnaOno Intimates, a lingerie company that makes products with breast cancer patients in mind. Designer Dana Donofree started AnaOno in 2015 after battling breast cancer and having both of her breasts removed. She eventually underwent reconstructive surgery, but realized traditional bras were hard for her to wear. Article by Korin Miller for WomensHealth vi

THE NEW OFFENSIVE ON ALZHEIMER’S DISEASE: STOP IT BEFORE IT STARTS

From Newsweek by ELIE DOLGIN "This aggressive attempt to prevent Alzheimer’s rather than treating it is the most exciting new development in decades, as well as a radical departure for researchers and the pharmaceutical industry. Traditionally, drug companies have tested their therapies on patients who already have memory loss, trouble thinking and other signs of dementia. It’s been a losing tactic: More than 99 percent of all Alzheimer’s drugs have failed tests in the clinic, and the few that have made it to the market only ameliorate some symptoms. Not a single medicine has been shown to slow the relentless progression of the disease. But with this new approach, even partial success—an app

A ‘trick’ to finding breast cancer goes viral on Facebook–here’s what was missing from the message

"This week a Facebook post from user Hayley Browning on her “trick” to finding breast cancer went viral, garnering 150,000+ shares, and 22,000 comments in just a handful of days. “3 weeks ago, I was diagnosed with Breast Cancer. I could only feel the lump whilst lying down and it completely disappeared standing up. …this is a call out to all women to check for lumps lying down, as well as standing up,” her post states. In the era of heated political rhetoric, it’s impressive to see a post about basic health information do so well. Yet–you knew there was a yet, didn’t you?–we also cringed just a little, especially as we skimmed CBS News’s write-up on the post. We expected that their story wou

Alzheimer’s disease researchers solve mystery of beguiling protein

Leading neuroscientists have clarified the role of a controversial immune system protein in Alzheimer’s disease, showing it has opposing effects in early and late stages of the disease. Their discovery unites previous studies that left researchers conflicted and showed the protein both exacerbates and ameliorates disease symptoms. The updated model of disease progression, published in the Journal of Neuroscience, also highlights the need to align certain therapies with disease stages when treating the 1 in 9 Americans over 65 living with Alzheimer’s. The protein in question is TREM2, or triggering receptor expressed on myeloid cells 2. It sits on the surfaces of immune cells in the brain and

UCSF study: ‘Dense breasts’ exceed all other breast cancer risk factors

"A new UC San Francisco-led study shows that women with “dense breasts” are at increased risk for breast cancer compared with women with a family history of the disease, their own history of benign lesions, or a first full-term pregnancy over age 30. The findings were published Thursday in the journal JAMA Oncology. Led by Natalie Engmann, a Ph.D. candidate in UCSF’s Department of Epidemiology and Biostatistics, and Dr. Karla Kerlikowske, the researchers believe their work is the first large-scale study to measure the development of breast cancer according to the degree of breast density. About 40 percent of women in the U.S. over age 40 have dense breast tissue, which makes it harder to ide

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