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Research team shrinks breast cancer tumors in mice with targeted therapy

A team of researchers led by Worcester Polytechnic Institute (WPI) Provost Wole Soboyejo has identified targeted drugs that reduced the sizes of hard-to-treat breast cancer tumors in mice without inducing the toxic side effects that are typically associated with conventional chemotherapy. ARTICLE

BLOOD TEST DETECTS ALZHEIMER’S DISEASE

The blood test accurately measures one of the proteins—P-tau181—implicated in Alzheimer’s disease (AD), according to a new study. Blood P-tau181 indirectly measures tau hyperphosphorylation in the brain, which is one of the hallmarks of the disease along with the clumpy plaques caused by the protein amyloid β. ARTICLE

Diet high in fiber linked to lower breast cancer risk

Women who eat a diet rich in fiber may have a lower risk of breast cancer, a review of studies has found. Harvard University researchers analyzed 20 published papers about fiber consumption and the incidence of the disease, and then identified study participants who ate the most and the least fiber. ARTICLE

What to eat to reduce your risk of Alzheimer’s disease

Would you like reduce your risk of cognitive impairment, Alzheimer’s disease, and dementia? Researchers from around the world having been studying a variety of different factors that might reduce these risks and keep the brain healthy.

Who Benefits from Herceptin and Other Anti-HER2 Cancer Therapies?

HER2-positive breast cancer may be a misnomer, according to a growing body of evidence that one of the most widely recognized oncogenes, HER2, may not be the primary driver of the disease. The research, which comes from several groups including Genentech, makers of the prevailing anti-HER2 treatment, has researchers questioning whether current clinical guidelines for classifying and treating breast cancer may be off the mark. New classification schemes may better identify those patients more likely to benefit from anti-HER2 treatment, or point to therapies that might be more effective. Article

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