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Alzheimer’s disease may start in the gut and spread to the brain

Alzheimer’s disease may be caused by the abnormal build-up of a protein in the gut that gradually spreads to the brain, according to research in mice.

In people with Alzheimer’s disease, a protein called beta-amyloid clumps together in the brain to form plaques that disrupt normal brain processes. Beta-amyloid deposits have also been found in the guts of people who died with the condition, but they have been largely overlooked.

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