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PET scans ID biomarkers that could spare breast cancer patients from chemotherapy

Researchers from Johns Hopkins University School of Medicine in Baltimore, Maryland, have used PET scans to identify biomarkers that may help predict which breast cancer patients can avoid chemotherapy treatment. The team published its findings online in the February issue of the Journal of Clinical Oncology.

Roughly 8 percent of all breast cancers are estrogen receptor (ER)-negative, HER2-positive. Standard treatment includes surgery to remove the tumor, antibody therapy to cut off the ability of the HER2 gene to support the growth of breast cancer cells and chemotherapy to kill the cancer cells.

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