Researchers Say They May Have Found ‘Big Bang’ in Alzheimer’s Disease

People in midlife may find some gray hair on the outside of their heads while they develop a new fear about what’s inside their skull.

One of the biggest worries is developing dementia.

Now, a leading dementia expert says his team has discovered a “big bang” of Alzheimer’s disease — the exact point at which a healthy protein becomes toxic but hasn’t yet formed deadly tangles in the brain.

A study from the University of Texas Southwestern’s O’Donnell Brain Institute offers a novel insight into the shape-shifting nature of a tau molecule just before it begins sticking to itself to form larger aggregates.

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