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New Research Sheds More Light On Alzheimer's in Women

Women seem to be dominating the headlines recently, with the triumphant U.S. women’s team World Cup Soccer win and the focus of attention on Capitol Hill’s female legislators. However, one area where women are leading is not a reason for applause: the disproportionate impact of Alzheimer’s disease on the female population. Full Article HERE

New discovery could open up PARP inhibitors to more cancer patients

PARP inhibitors have transformed treatment for breast and ovarian cancers, but their use has been limited to the small proportion of patients who have BRCA mutations. New research out of UT Southwestern Medical Center has uncovered a mechanism by which the drugs attack cancer, suggesting they could be put to use in many more patients. The FDA has approved four PARP inhibitors, starting with AstraZeneca’s Lynparza in 2014 for heavily treated ovarian cancer. These drugs block PARP enzymes, shutting down DNA repair and killing cancer cells. They work in tandem with BRCA mutations, which also hamper DNA repair in cancer cells, delivering a one-two punch that cancer cells cannot survive. Full art

Avoiding Alzheimer’s

One of the biggest changes in adult development over the past 50 years is that it has been extended farther and farther. All over the world, life expectancies are rising as medical interventions become more effective at defeating diseases and prolonging life. Right now, life expectancy at age 65is about 22 years in most developed countries, longer than ever before, and it’s rising in developing countries as well. Full Article HERE

New Nanoparticles to Stop Growth of HER2-Positive Breast Cancer

HER2 (human epidermal growth factor receptor 2) is a protein that is associated with some particularly aggressive forms of breast cancer. The presence of high concentrations of this protein seems to lead to the growth of tumors, so inactivating HER2 may help to stop the spread of certain strains of cancer in the body. Full article HERE

New clues on why women’s Alzheimer’s risk differs from men’s

New research gives some biological clues to why women may be more likely than men to develop Alzheimer’s disease and how this most common form of dementia varies by sex. At the Alzheimer’s Association International Conference in Los Angeles on Tuesday, scientists offered evidence that the disease may spread differently in the brains of women than in men. Other researchers showed that several newly identified genes seem related to the disease risk by sex. Full article HERE

Blood Test May Be Able To Predict Breast Cancer Relapse

A newly-developed blood test may be able to predict if people with breast cancer are likely to relapse at the point they are initially diagnosed by looking at markers of immune system function. The work, led by researchers from City of Hope in California was published in Nature Immunology and looks at immune biomarkers in blood to figure out whether breast cancers are likely to come back even after treatment. Full article HERE

Breast Cancer: Financial And Estate Planning Check-Up

A diagnosis of breast cancer will affect every aspect of your life, not just health issues. It will affect finances, life expectancy, insurance coverage, and estate planning steps. While comprehensive proactive planning to address some of these issues before a specific diagnosis is received would be ideal, the reality is that too few consumers address these matters until the reality of cancer occurs. Full article HERE

DOES POOR SLEEP IN YOUR 50S WARN OF ALZHEIMER’S?

The new finding highlights the importance of sleep at every age to maintain a healthy brain into later life. “Insufficient sleep across the lifespan is significantly predictive of your development of Alzheimer’s disease pathology in the brain,” says the study’s senior author, Matthew Walker, a sleep researcher and professor of psychology at the University of California, Berkeley. “Unfortunately, there is no decade of life that we were able to measure during which you can get away with less sleep. There is no Goldilocks decade during which you can say, ‘This is when I get my chance to short sleep.'” Full article HERE

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