Researchers See Uptick in Size of Breast Cancer Tumors at Diagnosis

Researchers say the size of breast tumors at diagnosis has decreased since routine screening came along, but they’re getting bigger. Breast tumors are significantly smaller at diagnosis today than they were in the early 1980s, thanks in large part to better screening. However, experts have changed screening guidelines in recent years to recommend younger women wait to start annual mammograms in the hopes of reducing overtreatment for an irregular result or false positive on a mammogram. These changes have been controversial. Some experts are worried that new guidelines could mean missing cancer tumors. Now, new research has found that doctors are seeing a small increase in tumor size in cert

Americans With Alzheimer's Now Number 5.7 Million

The estimated number of Americans with Alzheimer’s disease and other dementias has risen to 5.7 million, from 5.5 million in 2017, according to a report released today by the Alzheimer’s Association. That's an increase of roughly 3.6% and largely reflects the aging of the boomer generation. By 2025, the 2018 Alzheimer's Disease Facts and Figures report projects, 7.1 million Americans aged 65 and older will have Alzheimer’s, and by 2050, some 13.8 million. Accurate counting of Alzheimer’s cases is difficult, said Ron Brookmeyer, professor of biostatistics at the UCLA Fielding School of Public Health, who was not involved with the new report. There is no national surveillance of the disease an

How 23andMe Quelled FDA Concerns About DTC Breast Cancer Gene Test

When the FDA approved 23andMe’s direct-to-consumer test for some BRCA1/BRCA2 gene mutations on March 6, it did so with caveats. The test, which will be wrapped into a larger health-risk test offered by the company, only detects three out of more than 1,000 variants that have been linked to an increased risk of breast, ovarian and other tumors, the FDA noted in its announcement of the approval. The agency also said it imposed “special controls” on 23andMe to “provide reasonable assurance of safety and effectiveness for this test.” Nonetheless, the approval set off a debate in the medical community about whether the company is acting responsibly in offering a DTC genetic test that could reveal

Alzheimer's costs Americans $277 billion a year, and rising

Sharp increases in Alzheimer's disease cases, deaths and costs are stressing the U.S. health care system and caregivers, a new report reveals. About 5.7 million Americans have Alzheimer's disease -- 5.5 million of them aged 65 and older. By 2025, the number of seniors with Alzheimer's could reach 7.1 million, up nearly 29 percent. And, if no new treatments are found, that number could hit 13.8 million by 2050, according to the new report on Alzheimer's disease facts and figures, published online March 20 by the Alzheimer's Association. Every 65 seconds, someone in the United States develops Alzheimer's disease. By 2050, that will occur every 33 seconds, the experts said. While deaths from ot

Study Reveals a Strategy to Reduce Heart Damage Linked to the Breast Cancer Drug Herceptin

Breast cancer patients who take either of two heart medicines while undergoing treatment with Herceptin (trastuzumab) were not protected from the cardiac damage that is a common side effect of Herceptin therapy. This is according to a large, randomized clinical trial presented Sunday, March 11, 2018, at the American College of Cardiology’s 67th Annual Scientific Session in Orlando, Florida. But the patients did benefit from either of the two common heart drugs if they had already undergone treatment with drugs called anthracyclines before starting Herceptin, or if they were being treated with anthracyclines and Herceptin at the same time. Anthracyclines, such as Adriamycin or Rubex (doxorubi

Irish researchers make massive Alzheimer’s breakthrough

A small team of scientists at the Royal College of Surgeons in Ireland (RCSI) are behind the discovery. According to the researchers, changes of a small molecule in the blood can diagnose the disease at a stage when other symptoms are mild. When it comes to Alzheimer’s, early detection is crucial to treatment of the disease and patients’ quality of life. In the last twenty years, no new therapies to treat the disease at its advanced stages have passed clinical trials. For treatments to be successful, early stages preceding full onset of Alzheimer’s need to be targeted - hence why this Irish breakthrough is major international news. Lead researcher physiologist Dr Tobias Engel stated, “People

FDA OKs First At-home Genetic Test for Breast Cancer Risk

U.S. regulators have approved the first genetic test a woman can take at home to check her risk of developing breast cancer — but its focus is narrow, essentially applying only to Ashkenazi Jews. No doctor’s prescription will be needed for the test, which was developed by 23andMe. The test assesses the three most common BRCA gene mutations found in people of Eastern European Jewish descent. The U.S. Food and Drug Administration noted that while the mutations are present in roughly 2% of these women, they rarely occur in other ethnic populations. Prevalences in non-Jews range from 0% to 0.1%. Also, there are more than 1,000 BRCA mutations. So a negative test result, either in women of Ashkena

Can exercise help fight Alzheimer's disease?

Some people with a family history of Alzheimer’s are trying to prevent it, and not by popping pills. Alzheimer’s disease already impacts more than 5 million Americans. Some of them inherited the disease from a parent or other relative. Now, the question is, can it be prevented? And what is the key? She wants to keep her heart and fitness in top notch shape, but Carol Hall thinks working out may also strengthen her defenses against Alzheimer’s disease. It’s already hit her mother and her grandmother, and that family connection puts her at greater risk. She’s part of a national study to see if aerobic exercise, blood pressure and cholesterol-lowering drugs can prevent, or at least slow down, t

Twenty-four previously unknown mutations that raise a woman's risk of developing breast cancer h

Twenty-four previously unknown mutations that raise a woman's risk of developing breast cancer have been identified by scientists. The 'ground-breaking' findings today provide an answer to thousands of victims of whom the disease runs in their family. Mutations in known breast cancer genes are identified in only 20 per cent of women offered genetic testing for familial breast cancer. But Australian scientists believe the new discovery 'unlocks a big part of the puzzle' and argue they should be looked for in tests. To read the full article, click HERE Written by STEPHEN MATTHEWS FOR MAILONLINE (Shutterstock)

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