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The surprising link between air pollution and Alzheimer’s disease

"With environmental regulations expected to come under heavy fire from the Trump administration, new research offers powerful evidence of a link between air pollution and dementia risk. For older women, breathing air that is heavily polluted by vehicle exhaust and other sources of fine particulates nearly doubles the likelihood of developing dementia, finds a study published Tuesday. And the cognitive effects of air pollution are dramatically more pronounced in women who carry a genetic variant, known as APOE-e4, which puts them at higher risk for developing Alzheimer’s disease. In a nationwide study that tracked the cognitive health of women between the ages of 65 and 79 for 10 years, those

Nearly half of Breast Cancer Patients Have Severe Treatment Side Effects

"Many women being treated for breast cancer suffer from severe treatment side effects even when they don't receive chemotherapy, a recent study suggests. For the study, researchers surveyed 1,945 women diagnosed with early-stage breast cancer about the severity of seven treatment side effects: nausea and vomiting, diarrhea, constipation, pain, arm swelling, shortness of breath and breast skin irritation. Overall, 45 percent of participants reported severe or very severe forms of at least one of these side effects. When women got chemotherapy, the odds of severe side effects were twice as high, though the side effects were just 30 percent more likely when chemo was paired with radiation." To

New Alzheimer’s documentary is an ‘urgent wake-up call’

"If you care for someone with Alzheimer’s disease or know someone who does, even if you’re simply concerned about your memory, a new documentary airing Wednesday on PBS is a must watch. "Alzheimer’s: Every Minute Counts," scheduled to air at 10 p.m. on WPBT2, is touted by its makers as "an urgent wake-up call about the national threat posed by Alzheimer’s disease," a progressive, degenerative brain disease that destroys memory and thinking. More than five million Americans suffer from Alzheimer’s and that number is projected to jump 55 percent by 2030. By 2050, 14 million Americans could have Alzheimer’s, according to the Alzheimer’s Association — much of the rise due to the growing number o

Breast Cancer Is Hard To Treat: What Protects These Tumor-Iniating Cells?

"Breast cancer is one of the types of cancer that is very difficult to treat because the tumor cells may come back and recur. A team of scientists has identified a protein that may play a pivotal role in maintaining a population of tumor-initiating cells (TICs), which are cells resistant to treatment. Investigators at the Massachusetts General Hospital have recognized a protein, called G3BP2, affects the survival and proliferative potential of breast cancer cells. This protein is responsible for regulating the ratio of TICs to non-TICs within a tumor. "We also found that G3BP2 regulates breast tumor initiation in a way that leads to the increased expression of Oct-4 and Nanog, transcription

Do Patients Want to Know Whether Alzheimer Disease Awaits Them?

"Interest in predictive testing for Alzheimer disease (AD) and advanced care planning is high among the general public, according to results of a survey-based cross-sectional study within the National Institute on Aging’s Health and Retirement Study (HRS).1 Although research on accurate prediction of AD has been ramped up, predictive testing has yet to be made available—and the question looms as to whether a person would want to live with the knowledge that AD is waiting in the wings. Because informal surveys have shown that the public has a keen interest in knowing AD risk status despite the prognosis, researchers from Stanford University and the University of California at San Francisco an

12 key signs of breast cancer, as seen in viral image of lemons

"A breast cancer awareness campaign went viral after a 38-year-old patient shared the image of 12 lemons, each showing a different sign of breast cancer, on social media. Erin Smith Chieze originally found a similar image two years ago, and credited it with saving her life after she used it for reference and was subsequently diagnosed with stage 4 breast cancer. Her January 10 Facebook post was shared over 33,000 times. “I knew all about self exams, but a picture of what to look for keyed me into knowing I had a terminal disease,” Chieze wrote in the post. The post shows an image from the Worldwide Breast Cancer Organization’s Know Your Lemons campaign, of 12 lemons each bearing a different

Promising Discovery for a Non-Invasive Early Detection of Alzheimer's Disease

"A discovery of high relevance in medical research will be published in Volume 55, number 4 of December 2016 of the Journal of Alzheimer's Disease (JAD), entitled "Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease." This paper has been highlighted as one of the most important contribution to this field. The paper stems from a fruitful collaboration between the neuroscience laboratory from the International Center for Biomedicine (ICC) under the leadership of Dr. Ricardo Maccioni and the research teams of Drs. Andrea Slachevsky, Faculty of Medicine, University of Chile, together with Drs. Oscar Lopez and James Becker from University of Pittsburgh, School

Thousands Give DNA To Crowdsourced Breast Cancer Research Project In Massachusetts

"Thousands of metastatic breast cancer patients nationwide have given researchers access to their tumors and DNA in the hopes it will lead to breakthrough treatments and therapies for one of the most deadly forms of cancer. As the groundbreaking study enters its second year, more than 2,900 women and men have signed on to participate in the Metastatic Breast Cancer Project (MBCproject) since it launched October 20, 2015. Spearheaded by the Broad Institute of the Massachusetts Institute of Technology and Harvard, the project aims to find possible new treatments for the disease by examining patient-submitted DNA and medical records. Thirty-eight patients from Connecticut have expressed interes

Penn State Researcher Hopes to Cure Alzheimer’s Disease

"Every 66 seconds in the United States someone develops Alzheimer’s disease, according to the Alzheimer’s Association. But a researcher at Penn State believes he can cure the deadly disease. During his recent 50th birthday party, Gong Chen stood in front of a group of friends, family members and colleagues and delivered a declaration for the “second half” of his life. “Everyone was there, even my mother came from China to be at the party,” Chen said. “I told them I now know the purpose of my life is to find a cure for Alzheimer’s and dementia.” To read the full article, click HERE. (photo credit: Nabil K. Mark Centre Daily Times)

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